| 产品详情 |
| Edit |   |
|---|
| Product Name | ASK1, Recombinant, Human, GST-Tag (Apoptosis Signal-regulating Kinase 1, MAP3K5, MEKK5, MAPKKK5) |
|---|
| Description | Purified (~70-90%). ASK1, also known as MAPKKK5, activates MKK3, MKK4 (SEK1), and MKK6. Overexpression of ASK1 induces apoptotic cell death, and ASK1 is activated in cells treated with tumor necrosis factor-alpha. ASK1 interacts with members of the TRAF family and is activated by TRAF2 in the TNF-signaling pathway. After activation by TRAF2, ASK1 activates MKK4, which in turn activates JNK. Thus, ASK1 is a mediator of TRAF2-induced JNK activation. Source: Recombinant protein corresponding to human ASK1, fused to GST-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~60kD Specific Activity: 97nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Accession: NM_005923 |
|---|
| Catalog # | 499792 |
|---|
| Price | |
|---|
| Order / More Info | ASK1, Recombinant, Human, GST-Tag (Apoptosis Signal-regulating Kinase 1, MAP3K5, MEKK5, MAPKKK5) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|