产品详情 |
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Product Name | SSR 69071 |
Description | A potent inhibitor of neutrophil elastase (Ki = 0.0168 nM for the human enzyme); selective for human neutrophil elastase over rat, mouse, and rabbit elastases (Kis = 3, 1.8, 58 nM, respectively); inhibits human neutrophil elastase ex vivo in mouse BAL fluid (ED50 = 10.5 mg/kg, p.o.); reduces acute lung hemorrhage induced by human neutrophil elastase in mice (2.8 mg/kg, p.o.); reduces carrageenan- and human neutrophil elastase-induced paw edema in rats (ED30s = 2.2 and 2.7 mg/kg, respectively); reduces cardiac infarct size in a rabbit model of ischemia-reperfusion injury, |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SSR69071 HLE |
Gene, Accession, CAS # | CAS: 344930-95-6 |
Catalog # | 21477-10 |
Price | |
Order / More Info | SSR 69071 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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