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| Product Name | Phosphoinositide 3-kinase p110 alpha, p85 alpha, Recombinant, Bovine (PI3K) |
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| Description | Purity ≥ 95% by SDS-PAGE. The PI3KαR916P protein is a catalytically inactive mutant of PI3Kα in which Arg916 was mutated to Pro. This recombinant catalytically inactive protein can be used as a negative control in any kind of PI3Kα kinase activity studies. Recombinant full length PI3KαRP mutant carries a N-terminal GST-Tag and was purified by affinity chromatography. The GST-Tag facilitates the protein's application in typical GST pull-down assays. Phosphoinositide 3-kinases (PI3Ks) phosphorylate phosphatidylinositols (PIs) at their 3?-OH position generating lipid second messengers and thereby regulate numerous biological processes including cell growth, differentiation, survival, proliferation, migration and metabolism. On the basis of structural similarities and substrate specificity, the PI3K family can be subdivided into three classes termed I, II, and III. All human class I members are heterodimers consisting of a catalytic subunit (MW approx. 110kD) and a |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_174574 |
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| Catalog # | P4073-38J |
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| Order / More Info | Phosphoinositide 3-kinase p110 alpha, p85 alpha, Recombinant, Bovine (PI3K) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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