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| Product Name | Paired Immunoglobulin-Like Type 2 Receptor alpha, Recombinant, Mouse (PILR-alpha, PILRa) |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin ≤ 1EU. PILR-alpha (paired immunoglobulin-like type 2 receptor-alpha; also FDF03) is one of two members of a small family of immunoregulatory Ig-superfamily receptors (1, 2). It is a counterpart to PILR-Beta and it likely gave rise to PILR-Beta through gene duplication and rearrangement (1). The PILRs represent one of many pairs of Ig-like domain-containing receptors that participate in immune regulation. PILR-alpha and -Beta should not be confused with the similarly named PIRs (also paired immunoglobulin-like receptors ), or the functionally-related SIRP and ILT/LILR/CD85/LIR family of receptors (2). While PIRs, ILTs and SIRPs contain three to six Ig-like domains in their extracellular region, PILR-alpha and -Beta show only one Ig-like region in their extracellular domain (ECD) (1, 2). Mouse PILR-alpha is a monomeric, 271 amino acid (aa) type I transmembrane (TM) protein (3). It contains a 167 aa ECD, a 2 |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_705730 |
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| Catalog # | P2150-48 |
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| Order / More Info | Paired Immunoglobulin-Like Type 2 Receptor alpha, Recombinant, Mouse (PILR-alpha, PILRa) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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