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| Product Name | MASP1, Recombinant, Human, aa20-699, His-Tag (Mannan-binding Lectin Serine Protease 1) |
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| Description | Purity ~85% (SDS-PAGE). Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Source: Recombinant protein corresponding to aa20-699 from human MASP1, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~79.03kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Complement factor MASP-3, Complement-activating component of Ra-reactive factor Mannose-binding lectin-associated serine protease 1, MASP-1, Mannose-binding protein-associated serine protease Ra-reactive factor serine protease p100, RaRF Serine protease 5 Cleaved into the following 2 chains: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain |
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| Gene, Accession, CAS # | SwissProt: P48740 |
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| Catalog # | 374155 |
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| Order / More Info | MASP1, Recombinant, Human, aa20-699, His-Tag (Mannan-binding Lectin Serine Protease 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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