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| Product Name | Quinacrine analog 34 |
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| Description | Purity >98%. Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 µM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 µM) to inhibit autophagy. At a minimum concentration of 0.5 µM, this compound has been shown to increase the protein levels of the autophagy biomarker LC3-II and to induce lysosome deacidification. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-chloro-1,2,3,4-tetrahydro-N -[2-(4-methyl-1-piperazinyl)ethyl]-9-acridinamine |
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| Gene, Accession, CAS # | CAS: 1411646-44-0 |
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| Catalog # | LS-H9626 |
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| Order / More Info | Quinacrine analog 34 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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