| 产品详情 |
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| Product Name | mGluR5,1a peptide(Metabotropic Glutamate Receptor) |
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| Description | Sequence (linear): C-Terminal 13 amino acids LIIRDYTQSSSSL of rat mGluR5, Metabotropic Glutamate Receptor 5. Corresponding antibody M3884-79B shows reactivity to mGluR1a with a species reactivity to human, rat, mouse and feline. Metabotropic glutamate receptors have been classified into three groups. In general, class I receptors (mGluR1 and mGluR5) mediate the excitation of neurons, whereas activation of class II (mGluR2 and mGluR3) and class III (mGluR4a, mGluR7a, mGluR7b and mGluR8) results in a depression of synaptic transmission. Class I mGluRs are localized in the postsynaptic membrane and are positively coupled to phospholipase C (PLC). Class II and class III mGluRs localized to the presynaptic membrane and are negatively coupled to adenylate cyclase. It has been speculated that mGluR2 and/or mGluR3 may play a role in the modulation of the mossy terminal function. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M3884-79C |
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| Price | |
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| Order / More Info | mGluR5,1a peptide(Metabotropic Glutamate Receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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