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Product Name | Cytidine Deaminase (CDA) (AA 1-146) (Active) protein (His tag) |
Description | Cytidine deaminase (CDA) is an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. CDA is one of several deaminases responsible for maintaining the cellular pyrimidine pool. CDA also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. CDA can form homotetramers and is generally expressed in granulocytes. Mutations in the CDA gene are linked to decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias Synonyms: Cytidine deaminase, Cytidine aminohydrolase, CDA, CDD |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CDA|cda|zgc:77948|DDBDRAFT_0188181|DDBDRAFT_0230205|DDB_0188181|DDB_0230205|CDD|2210401N16Rik |
Gene, Accession, CAS # | Gene ID: 978 |
Catalog # | ABIN805248 |
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Order / More Info | Cytidine Deaminase (CDA) (AA 1-146) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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