| 产品详情 |
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| Product Name | ACPT-I |
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| Description | An mGluR4a and mGluR8 agonist (EC50s = 7.2 and 8.2 µM, respectively); has no effect on mGluR1a or mGluR2; reduces cell death following oxygen-glucose deprivation in primary neuronal cultures using concentrations of 1-200 µM; reduces cell death in a rat model of middle cerebral artery occlusion when used at a dose of 30 mg/kg; reduces the incidence of clonic seizures in various seizure models in mice and rats (ED50s = 0.08-49.3 nM, i.c.v.); has anxiolytic-like effects in mice and rats that can be blocked by 5-HT1A and GABAA receptor antagonists |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ACPTI mGluR-4a 8 1a 2 anti-convulsant WAY100635 5HT 5HT1A GABA-A |
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| Gene, Accession, CAS # | CAS: 194918-76-8 |
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| Catalog # | 78010-1 |
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| Order / More Info | ACPT-I from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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