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| Product Name | Trefoil Factor 3, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE and HPLC). The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation. Recombinant human TFF3 is a 13.2kD homodimeric protein consisting of two 59aa chains, which includes a 40aa trefoil motif containing three conserved intramolecular disulfide bonds. Source: Recombinant protein corresponding to human Trefoil Factor 3, expressed in E.coli. Biological Activity: Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1-10ug/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Seq |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Trefoil Factor 3, Recombinant, Human (TFF3, Intestinal Trefoil Factor, hITF, Polypeptide P1.B, hP1.B, ITF, TFI) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149649 |
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| Order / More Info | Trefoil Factor 3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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