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| Product Name | Macrophage inflammatory protein 3 beta,, Recombinant, Rat, aa26-108 |
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| Description | Purity ~95% by (SDSPAGE). CCL19 (also known as Mip-3beta, ELC, CKbeta-11, Scya19 and Exodus-3) is a 9kD secreted member of the CC family of chemotactic cytokines (1-4). Cells known to express CCL19 are limited in number, and include activated monocytes (5), stromal cells in nodal T zones (6), CD8+ dendritic cells (DC) (6), vascular endothelial cells (7), visceral smooth muscle and mast cells (8), and thymic stromal cells (9). Rat CCL19 is synthesized as a precursor that is 1108 amino acids (aa) in length. The precursor contains a 25aa signal sequence plus an 83aa mature region (aa26-108) (10). The signature CC chemokine motif occurs at Cys33Cys34 and there are no potential N-linked glycosylation sites. It is unclear if rat CCL19 forms homodimers. Mature rat CCL19 shares 72% and 89% aa sequence identity with human and mouse CCL19, respectively (3, 4, 10). CCL19 is known to bind to CCR7 (3, 4), CCLR2/CRAM (L-CCR in rodent) (11, 12, 13) and CCX-CKR (14), with the last two receptors repre |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Macrophage inflammatory protein 3 beta,, Recombinant, Rat, aa26-108 (CCL19, MIP-3 beta, Mip-3beta, ELC, CKbeta-11, Scya19, Exodus-3) |
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| Gene, Accession, CAS # | Accession: NP_001102131 |
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| Catalog # | 145716 |
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| Order / More Info | Macrophage inflammatory protein 3 beta,, Recombinant, Rat, aa26-108 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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