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| Product Name | STAT3, Recombinant, Human, aa1-770, His-Tag (Signal Transducer and Activator of Transcription 3) |
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| Description | Purity ~90% (SDS-PAGE). Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic domain STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G. Source: Recombinant protein corresponding to aa1-770 from human STAT3, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~90.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Acute-phase response factor |
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| Gene, Accession, CAS # | SwissProt: P40763 |
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| Catalog # | 375431 |
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| Order / More Info | STAT3, Recombinant, Human, aa1-770, His-Tag (Signal Transducer and Activator of Transcription 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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