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| Product Name | Histone H2b, Recombinant, Human |
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| Description | Purified (~65%). Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. Source: Recombinant corresponding to aa2-126 from human Histone H2B, fused to His tag at N-terminal, expressed in E. coli. Molecular Weight: ~14.6kD Applications: Suitable for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Histone H2b, Recombinant, Human (Histone H2B Type 1-B, Histone H2B.f, H2B/f, H2BFF, Histone H2B.1, H2B.1, Histone Cluster 1 H2bb, HIST1H2BB, MGC119804) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137285 |
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| Order / More Info | Histone H2b, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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