| 产品详情 |
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| Product Name | AZD-6482 |
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| Description | Purity >98% by HPLC. AZD-6482 is a potent and selective inhibitor of PI 3-kinase Beta (PI 3-KBeta) (IC50 values are 0.69, 13.6, 47.8 and 136 nM for PI 3-KBeta, PI 3-Kd, PI 3-KGamma and PI 3-Ka, respectively). It displays 80-fold selectivity for PI3KBeta over PI3k-C2 and DNA-PK and more than 1,000-fold over other PI3K-related kinases. AZD6482 blocks Akt signaling and tumor growth in a large number of cancer cell lines, including those that are dependent on PI3KBeta activation or PTEN loss. A potent and selective inhibitor of PI 3-kinase Beta (PI 3-KBeta). (Biochemical) |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (-)-2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid |
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| Gene, Accession, CAS # | CAS: 1173900-33-8 |
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| Catalog # | LS-H3849 |
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| Price | |
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| Order / More Info | AZD-6482 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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