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| Product Name | Nampt, Recombinant, Human |
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| Description | Purity >90% (SDS-PAGE). Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kD adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. Biological Activity: Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Sequence: Intracellular human Nampt ( |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nampt, Recombinant, Human (His) (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotinamide Phosphoribosyltransferase) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45068 |
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| Order / More Info | Nampt, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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