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| Product Name | PAK1, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). PAK1 is a member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, CDC42 and RAC. PAK1 belongs to the Group I PAKs which also includes PAK2 and PAK3. PAK1 is a key regulator of the actin cytoskeleton, adhesion and cell motility. Inactive dimeric PAK1 is mainly cytosolic and interaction with the activators Cdc42-GTP and Rac1-GTP stimulates the kinase at the sites of cellular protrusions forming adhesions to the extracellular matrix. Source: Recombinant protein corresponding to human PAK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~95kD Specific Activity: 74nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PAK1, Recombinant, Human, GST-Tag (Serine/Threonine-protein Kinase PAK 1, Alpha-PAK, p21-activated Kinase 1, PAK-1, p65-PAK) |
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| Gene, Accession, CAS # | Accession: NM_002576 |
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| Catalog # | 500334 |
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| Order / More Info | PAK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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