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| Product Name | PAK6, Recombinant, Human, GST-Tag (Serine/Threonine-protein Kinase PAK 6, p21-Activated Kinase 5, PAK5) |
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| Description | Purified (~70-90%). PAK6 is a Ser/Thr protein kinase that is a member of the PAK (p21-activated kinase) family that are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 is highly expressed in the testis and prostate tissues and interacts with the androgen receptor (AR). In response to androgen, PAK6 cotranslocate into the nucleus with AR. PAK6 is weakly expressed in normal prostate epithelium but the expression is increased in primary and metastatic prostate cancer cells and is further increased in tumors that relapse after androgen deprivation therapy. Source: Recombinant protein corresponding to human PAK6, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~110kD Specific Activity: 137nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_020168 |
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| Catalog # | 500338 |
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| Order / More Info | PAK6, Recombinant, Human, GST-Tag (Serine/Threonine-protein Kinase PAK 6, p21-Activated Kinase 5, PAK5) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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