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| Product Name | TXK, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). TXK or RLK is a member of the TEC family of non-receptor tyrosine kinases. TXK is expressed in T-cells and is an important component of signaling pathways downstream of lymphocyte antigen receptor. TXK is phosphorylated in response to T-cell receptor stimulation and can be activated by phosphorylation by Src family kinases. However, TXK is phosphorylated independent of PI-3K activity. Excessive TXK protein expression is seen in patients with Behcet's disease. Over production of TXK leads to increased Th1 cell function that is involved in the pathogenesis of Behcet's disease. Source: Recombinant protein corresponding to human TXK fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~53kD Specific Activity: 18nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TXK, Recombinant, Human, GST-Tag (Tyrosine-protein Kinase TXK, Protein-tyrosine Kinase 4, RLK, TKL, BTKL, PTK4, PSCTK5, MGC22473) |
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| Gene, Accession, CAS # | Accession: NM_003328 |
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| Catalog # | 500526 |
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| Price | |
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| Order / More Info | TXK, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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