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| Product Name | Heat Shock Cognate Protein 70, Recombinant, Human (HSC70, HSP73) |
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| Description | Purity ~ 90% pure as determined by SDS-PAGE analysis. HSP70 genes encode abundant heat-inducible 70kD HSPS (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian cells was truncated, ATP binding activity was found to reside in an N-terminal fragment of 44kD which lacked peptide binding capacity. Polypeptide binding ability therefore resided within the C-terminal half (4). The structure of this ATP binding domain displays mul |
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| Size | 50ug, 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H1831-25H |
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| Price | |
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| Order / More Info | Heat Shock Cognate Protein 70, Recombinant, Human (HSC70, HSP73) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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