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| Product Name | Recombinant Human Yorkie homolog (YAP1) |
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| Description | 1-504. Full length. MW: 68.5 kDa. Purity >85% as determined by SDS-PAGE. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3MST2 and STK4MST1, in complex with its regulatory protein SAV1, ph |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [transcriptional coactivator YAP1 isoform 1; Transcriptional coactivator YAP1; transcriptional coactivator YAP1; Yes associated protein 1; Protein yorkie homolog; Yes-associated protein YAP65 homolog] |
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| Gene, Accession, CAS # | YAP1, Gene ID: 10413, Accession: NP_001123617.1 |
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| Catalog # | MBS717875 |
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| Order / More Info | Recombinant Human Yorkie homolog (YAP1) from MYBIOSOURCE INC. |
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| Product Specific References | WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. Komuro A., Nagai M., Navin N.E., Sudol M. J. Biol. Chem. 278:33334-33341(2003) |
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