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| Product Name | 8(9)-EET Ethanolamide |
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| Description | Purity >98%. Arachidonoyl ethanolamide (AEA; anandamide) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1 ) and peripheral cannabinoid (CB2 ) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism of AEA by COX-2, lipoxygenases, and cytochrome P450 (CYP450) enzymes has also been documented. (±)8(9)-EET ethanolamide is a CYP450 metabolite of AEA, although specific stereochemistry rather than a racemic mixture would likely ensue from enzymatic metabolism. Human liver microsomes metabolize AEA to 5,6-, 8,9-, 11,12-, and 14,15-EET ethanolamides in a time and protein concentration dependent manner. (±)8(9)-EET reduces glomerular filtration rate through cyclooxygenase dependent preglomerular vasoconstriction. The physiological actions of (±)8(9)-EET ethanolamide have not been examined. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(2-hydroxyethyl)-(±)8(9)-epoxy-5Z,11Z,14Z-eicosatrienoic amide, (±)8,9-EET Ethanolamide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H6289 |
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| Order / More Info | 8(9)-EET Ethanolamide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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