| 产品详情 |
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| Product Name | Salermide |
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| Description | Purity >98%. The sirtuins (SIRTs) are a family of NAD+ -dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 µM) by reactivating proapototic genes that are repressed by SIRT1. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide |
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| Gene, Accession, CAS # | CAS: 1105698-15-4 |
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| Catalog # | LS-H9813 |
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| Price | |
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| Order / More Info | Salermide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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