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| Product Name | CD278(ICOS)-muIg-Biotin |
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| Description | Information: The inducible costimulator (ICOS, T cell activation molecule H4) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Each secondary signal from CD28 or ICOS results in a discrete cytokine secretion profile displayed by the activated T cell.1 Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.2 Human GL50 is a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2), and |
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| Size | 0.025 mg |
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| Concentration | 0.5 mg/ml |
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| Applications | Flow Cytometry (FC/FACS), ELISA (EIA) |
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| Other Names | [Human CD278(ICOS)-muIg/Biotin Fusion Protein] |
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| Gene, Accession, CAS # | [CD278] |
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| Catalog # | MBS666804 |
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| Order / More Info | CD278(ICOS)-muIg-Biotin from MYBIOSOURCE INC. |
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| Product Specific References | Beier, K.C., R.A. Kroczek, et al. 2000, Eur J Immunol. 30(12):3707-3717. 2 Riley, J.L., C.H. June, et al. 2001, J. Immunol. 166: 4943-4948. 3 Ling, V., M. Collins, et al. 2000, J. Immunol. 164: 1653-1657. 4 Ling, V., M. Collins, et al. 2001, J. Immunol. 166: 7300-7308. 5 A.J. McAdam, et al, (2000) J Immunol 165: 5035-5040. |
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