| 产品详情 |
| Edit |   |
|---|
| Product Name | MN-64 |
|---|
| Description | Purity >98%. Tankyrases (TNKS) are poly-ADP-ribosyltransferases, which cleave NAD+ to produce nicotinamide and ADP-ribose, which is then covalently attached to an acceptor protein in a process known as poly(ADP-ribosyl)ation. MN-64 is a potent inhibitor of TNKS1 and TNKS2 (IC50 s = 6 and 72 nM, respectively). It is ineffective against several poly(ADP-ribosyl) polymerases (IC50 > 19 µM). Through its effects on TNKS, MN-64 inhibits signaling along the Wnt/Beta-catenin pathway in a cell-based reporter assay. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[4-(1-methylethyl)phenyl]-4H-1-benzopyran-4-one |
|---|
| Gene, Accession, CAS # | CAS: 92831-11-3 |
|---|
| Catalog # | LS-H8783 |
|---|
| Price | |
|---|
| Order / More Info | MN-64 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|