产品详情 |
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Antigenic Specificity | Caspase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, FCM, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 3 Polyclonal Antibody. • Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). |
Immunogen | KLH conjugated synthetic peptide derived from rat Caspase 3. Immunogen Range: 1-45/277 |
Other Names | Lice; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; IRP; Protein Yama; SREBP cleavage activity 1; SCA-1; Casp3; Cpp32 |
Gene, Accession # | Gene ID: 25402, SwissProt: P55213 |
Catalog # | bs-2593R |
Price | |
Order / More Info | Caspase 3 Antibody from BIOSS ANTIBODIES |
Product Specific References | Luo, Xiaoming, et al. (2015) Eur J Pharm Biopharm. PubMed: 26523356 // Duan, Xiaoxu, et al. (2016) Free Radic Biol Med. PubMed: 26878773 // Zhang, Xiaolin, et al. (2016) Iran J Pharm Res. PubMed: 27642320 |
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