| 产品详情 |
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| Antigenic Specificity | Caspase 8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 488 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P), IF(ICC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 8 Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and C |
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| Immunogen | KLH conjugated synthetic peptide derived from mouse Caspase-8 subunit p10. Immunogen Range: 430-482/482 |
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| Other Names | MACH; Mch5; FLICE; CASP-8; Caspase-8; Casp8 |
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| Gene, Accession # | Gene ID: 12370, SwissProt: O89110 |
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| Catalog # | bs-0052R-A488 |
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| Price | |
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| Order / More Info | Caspase 8 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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