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| Product Name | Positive Cofactor 4, aa1-127, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE). SUB1, also known as PC4, is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. SUB1 interacts with the activation domain of transcription factor IIA (TFIIA) and TATA-binding protein (TBP)-associated factors (TAFs) to directly bind to double stranded DNA. This protein induces both activation and repression of RNAPII basal transcription, depending on the presence or absence of these transcription factors and holoenzyme components. Source: Recombinant corresponding to aa1-127 of human SUB1 6x his tagged, expressed in E.coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MPKSKELVSS SSSGSDSDSE VDKKLKRKKQ VAPEKPVKKQ KTGETSRALS SSKQSSSSRD DNMFQIGKMR YVSVRDFKGK VLIDIREYWM DPEGEMKPGR KGISLNPEQW SQLKEQISDI DDAVRKL |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Positive Cofactor 4, aa1-127, Recombinant, Human (Activated RNA Polymerase II Transcriptional Coactivator p15, MGC102747, p14, PC4, SUB1, RPO2TC1, SUB1 Homolog) |
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| Gene, Accession, CAS # | Accession: NP_006704 |
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| Catalog # | P4695-40H |
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| Order / More Info | Positive Cofactor 4, aa1-127, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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