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Product Name | JP-1302 (hydrochloride) |
Description | An α2C-AR antagonist; selective for α2C-ARs over α2A- and α2B-ARs (Kis = 28, 3,150, and 1,470 nM, respectively); reduces immobility time in the forced swim test in mice at 1, 3, and 10 µmol/kg; reverses phencyclidine-induced decreases in prepulse inhibition of the acoustic startle response in rat at 5 mg/kg; dose-dependently reduces haloperidol-induced bradykinesia and catalepsy in mice; increases systolic blood pressure in rats at 0.3 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 80259-18-3 JP1302 α2-AR α2CAR α2AAR α2BAR |
Gene, Accession, CAS # | CAS: 1259314-65-2 |
Catalog # | 25974-1 |
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Order / More Info | JP-1302 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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