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| Product Name | Leukemia Inhibitory Factor, Recombinant, Human |
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| Description | Purity ~95% (HPLC and SDS-PAGE). Leukemia Inhibitory Factor (LIF) is a lymphoid factor which promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. Human LIF is a 19.7kD protein containing 181aa residues. The non-glycosylated, E. coli expressed, recombinant human LIF is indistinguishable from native LIF in its biological activities in vitro. Human and murine mature LIF exhibit a 78% sequence identity at the amino acid control. Human LIF is equally active on both human and mouse cells. Murine LIF is approximately 1000 fold less active on human cells, than hLIF. Source: Recombinant corresponding to human LIF expressed in E.coli. Biological Activity: Determined by the ability to induce differentiation of |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Leukemia Inhibitory Factor, Recombinant, Human (LIF, Differentiation-stimulating Factor, D Factor, Melanoma-derived LPL Inhibitor, MLPLI, INN=Emfilermin, HILDA) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 136921 |
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| Order / More Info | Leukemia Inhibitory Factor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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