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| Product Name | Leukemia Inhibitory Factor, Recombinant, Rat (LIF) |
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| Description | Purity ~85% (HPLC, SDS-PAGE). Leukemia Inhibitory Factor (LIF) is a lymphoid factor which promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. Rat LIF (rtLIF) is a 19.9kD protein containing 183aa residues that exhibits 91% aa sequence identity with murine LIF1. Analysis of the secondary structure of rat and murine LIF indicates a difference in the two dimensional structure of both proteins. Studies have shown that rtLIF is more effective in maintaining the undifferentiated phenotype of rat ES cells than similar concentrations of murine LIF Source: Recombinant protein corresponding to 183aa of rat LIF, expressed in E. coli. Molecular Weight: ~19.9kD Biological Activity: Determined by the ability to in |
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| Size | 5ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299441 |
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| Price | |
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| Order / More Info | Leukemia Inhibitory Factor, Recombinant, Rat (LIF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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