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| Product Name | Leptin, Recombinant, Mouse (LEP, Ob, Obesity Factor) |
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| Description | Purity ~95% (SDS-PAGE). Endotoxin: ≤0.1ng/ug. Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body's fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Murine Leptin is a 16kD protein containing 147 amino acid residues. Source: Recombinant mouse Leptin expressed in E. coli. Biological Actvity: Murine Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5ug Leptin/gm of body weight for 14 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | obese |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1670-10D |
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| Order / More Info | Leptin, Recombinant, Mouse (LEP, Ob, Obesity Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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