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| Product Name | Leptin, Recombinant, Mouse (LEP, Ob, Obesity Factor) |
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| Description | Purity ~98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug. Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body's fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Murine Leptin is a 16kD protein containing 147 amino acid residues. Source: Recombinant, mouse Leptin expressed in E. coli. Biological Activity: Determined in an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 mg leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls. |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | obese |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1670-10E |
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| Order / More Info | Leptin, Recombinant, Mouse (LEP, Ob, Obesity Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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