| 产品详情 |
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| Product Name | Leptin, Recombinant, Mouse |
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| Description | Highly purified. A synthetic 12 amino acid sequence from the mouse obese (Ob) gene. Obesity, a common nutritional disorder, is associated with diabetes, hypertension, hyperlipidemia, cancer and many other health related problems. At least five genes, Obese (ob), diabetes (db), fat (fat), agouti yellow (Ay), and tubby (tub) have been linked to obesity. Recently, Ob genes (mouse and human) have been cloned. Obese gene encodes an adipocyte-tissue derived secreted Ob protein/Leptin (167 amino acid, ~16kD) that controls body weight homeostasis. Exogenous administration of recombinant Ob protein can reduce food intake and body weight. However, Ob protein had no effect in db/db mice suggesting a defect in leptin signaling mechanism. The Obese receptors (Ob-R) have now been cloned from mouse choroid plexus and it is expressed in several tissues including hypothalamus. The Ob-R has been shown to be a product of db gene that has long been thought to encode the receptor for a weight-controlling h |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Leptin, Recombinant, Mouse (Obese Protein, Obesity Factor) (Ob, Obese Protein, Obesity Factor) (Control Peptide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1670-16G |
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| Order / More Info | Leptin, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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