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Antigenic Specificity | Glial Cell Derived Neurotrophic Factor (GDNF) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA,Blocking Antibody (Inhibition),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GDNF is a disulfide-linked homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFR a(a1-a4) receptors. GDNF specifically promotes dopamine uptake and survival and morphological differentiation of midbrain neurons. Using Parkinson's disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. |
Immunogen | GDNF antibody was raised in rabbit using highly pure recombinant human GDNF as the immunogen. |
Other Names | GDNF|gdnf|gdnfa|hfb1-gdnf|ATF1|ATF2|HFB1-GDNF|HSCR3|AI385739 |
Gene, Accession # | Gene ID: 2668 |
Catalog # | ABIN636726 |
Price | |
Order / More Info | Glial Cell Derived Neurotrophic Factor (GDNF) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |