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| Product Name | Fibroblast Growth Factor 21, Recombinant, Human (FGF-21) |
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| Description | Purity > 97%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin: < 1.0 EU per 1ug of the protein as determined by the LAL method. Human FGF-21 Fibroblast growth factor 21 (FGF-21) is a member of the FGF gene family, which currently contains 22 human members. Based on its structure, it is further classified as an FGF19 subfamily member. This subfamily includes FGF-19, -21, and -23. Like all other FGF subfamilies, FGF-19 subfamily members contain a 120 amino acid (aa) core FGF domain that exhibits a b-trefoil structure (1, 2). Unlike other FGF subfamilies, FGF-19 subfamily members apparently exhibit poor binding to ECM, resulting in highly diffusible molecules (3). The c-DNA for FGF-21 predicts a 209aa polypeptide that contains a 28aa signal sequence and a 181aa mature region (4). Notably, FGF-21, as well as FGF-19 shows limited binding to heparin (4). One potential alternate splice form has been reported. It shows a 43aa substitution for the C-terminal 12aa of the stan |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9NSA1 |
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| Catalog # | F4212-93 |
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| Order / More Info | Fibroblast Growth Factor 21, Recombinant, Human (FGF-21) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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