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| Product Name | JAK2, Recombinant, Human, GST-Tag (Janus Kinase 2) |
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| Description | Purified (~70-90%). JAK2 is a member of intracellular non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. JAK2 has two near-identical phosphate-transferring domains. One domain exhibits the kinase activity while the other stabilizes the JAK conformational structure. JAK2 is the predominant JAK kinase activated in response to several growth factors and cytokines such as IL-3, GM-CSF and erythropoietin. JAK2 has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon. Source: Recombinant protein corresponding to human JAK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~63kD Specific Activity: 145nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_004972 |
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| Catalog # | 500190 |
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| Order / More Info | JAK2, Recombinant, Human, GST-Tag (Janus Kinase 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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