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| Product Name | JAK1, Recombinant, Human, GST-Tag (Janus kinase 1, JAK1A, JAK1B) |
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| Description | Purified (~70-90%). JAK1 is a member of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. JAK1 bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein that is involved in the interferon-alpha/beta and -gamma signal transduction pathways. JAK1 plays an essential and nonredundant role in promoting biologic responses induced by a select subset of cytokine receptors, including those in which JAK utilization is thought to be nonspecific. Source: Recombinant protein corresponding to human JAK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~108kD Specific Activity: 22nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002227, SwissProt: P23458 |
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| Catalog # | 500189 |
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| Order / More Info | JAK1, Recombinant, Human, GST-Tag (Janus kinase 1, JAK1A, JAK1B) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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