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| Product Name | Macrophage Colony-stimulating Factor 1, active (CSF1), Recombinant, Human |
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| Description | Purity ≥95% as determined by SDS-PAGE and HPLC. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. (ECO:0000269|PubMed:16337366, ECO:0000269|PubMed:19934330, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061). Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine M-NFS-60 cells |
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| Size | 2ug, 10ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CSF-1, MCSF, Lanimostim |
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| Gene, Accession, CAS # | CSF1_HUMAN, SwissProt: P09603 |
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| Catalog # | 348167 |
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| Order / More Info | Macrophage Colony-stimulating Factor 1, active (CSF1), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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