| 产品详情 |
| Edit |   |
|---|
| Product Name | Caspase-14, Recombinant, Human, aa153-240, GST-Tag (CASP14) |
|---|
| Description | Purity ~85% (SDS-PAGE). Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum. Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin. In vitro has a preference for the substate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF. Involved in processing of prosaposin in the epidermis. May be involved in retinal pigment epithelium cell barrier function. Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD Source: Recombinant protein corresponding to aa153-240 from human Caspase-14, fused to GST-Tag at N-terminal, expressed in E. coli. AA |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: P31944 |
|---|
| Catalog # | 372584 |
|---|
| Price | |
|---|
| Order / More Info | Caspase-14, Recombinant, Human, aa153-240, GST-Tag (CASP14) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|