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| Product Name | Caspase 9, Recombinant, Human (ICE-LAP6, Mch6, Apaf 3) |
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| Description | Caspase-9 (also know as Ice-Lap6 and Mch6) is a member of the interleukin-1b converting enzyme (ICE) family of cysteine proteases. Similar as other caspases, caspase-9 also exists in cells as an inactive proenzyme. During the initiation of apoptosis the proenzyme is processed at aspartate residues to form active caspase-9. As one of the initiator caspases, active caspase-9 functions to trigger the activation of downstream effector caspases and further leads to disassembly of cell structures. The active recombinant human caspase-9 was expressed in E. coli. The expressed caspase-9 spontaneously undergoes autoprocessing to yield the subunits characteristic of the native enzyme. In combination with caspase-9 activity assays, the active recombinant caspase-9 is useful in screening caspase inhibitors for pharmaceutical applications. The recombinant enzyme can also be used as a positive control in caspase-9 assays. 6x His tags are located on the N and C termini. Specific Activity: 400 U/mg Un |
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| Size | 25U, 100U |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2088 |
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| Order / More Info | Caspase 9, Recombinant, Human (ICE-LAP6, Mch6, Apaf 3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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