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| Product Name | Caspase-8, Recombinant, Mouse (Casp8, CASP-8, Caspase-8 Subunit p18, Caspase-8 Subunit p10) |
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| Description | Purity ~95% (SDS-PAGE). Caspase-8 (also know as FLICE, MASH, Mch5) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-8 also exists in cells as an inactive proenzyme. During apoptosis procaspase-8 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-8 consists of large and small subunits which associate to form the active enzyme. Active caspase-8 has been shown to activate caspase-3 leading to degradation of a variety of cellular target proteins during apoptosis. The recombinant active mouse caspase-8 was expressed in E. coli. The active caspase-8 is routinely tested for its ability to enzymatically cleave these two substrates Ac-IETD-pNA or Ac-IETD-AFC. Source: Recombinant protein corresponding to mouse Caspase-8, expressed in E. coli. Biological Activity: ~5000units/mg |
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| Size | 25U, 100U |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169643 |
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| Order / More Info | Caspase-8, Recombinant, Mouse (Casp8, CASP-8, Caspase-8 Subunit p18, Caspase-8 Subunit p10) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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