| 产品名称 |
AURORA B, Recombinant, Human, GST-Tag (AURKB, AIK2, AIM1, ARK2, AurB, IPL1, AIM-1, STK12) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | AURORA B, Recombinant, Human, GST-Tag (AURKB, AIK2, AIM1, ARK2, AurB, IPL1, AIM-1, STK12) |
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| Description | Purified (~70-90%). AURORA B is a member of the Aurora kinase family that associates with microtubules during chromosome movement and segregation. AURORA B localizes to the microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURORA B inhibits the microtubule depolymerizing activity of mitotic centromere-associated kinesin (MCAK) by phosphorylating MCAK on Ser92. This phosphorylation also regulates MCAK translocalization from kinetochores to the centromere. AURORA B has been identified as a target for the development of new anticancer agents since inhibition of AURORA B gives rise to the more pronounced antiproliferative phenotype. Source: Recombinant protein corresponding to human AURORA B, fused at GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~68kD Specific Activity: 162nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_004217 |
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| Catalog # | 499795 |
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| Price | |
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| Order / More Info | AURORA B, Recombinant, Human, GST-Tag (AURKB, AIK2, AIM1, ARK2, AurB, IPL1, AIM-1, STK12) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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