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Antigenic Specificity | Thyroid Hormone Receptor, alpha (THRA) (Isotype a1), (Isotype a2) |
Clone | 1718 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TR 1 and TR 2. TRa1, TR 1 and TR 2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005). Anti-Thyroid Hormone Receptor, a1/a2-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~50k TR-a1 and the ~58k TR-a2 protein. |
Immunogen | n/a |
Other Names | EAR1|THRA1|THRAL|ear-1|hRev|ERBA1|Thra1|6430529J03Rik|AW259572|Erba|Nr1a1|Rvr|T3R[a]|T3Ralpha|Thra2|Thra|nr1a1|thra1|TR[a]1|thra|thral|tra|tra1|wu:fb59g07|Nr1a2|T3R[b]|T3Rbeta|Thrb1|Thrb2|c-erbAbeta|AR7|CHNG6|EAR7|ERB-T-1|ERBA|NR1A1|THRA2|c-ERBA-1|C-ERBA-ALPHA|C-ERBA ALPHA1|TRalpha|c-erba|erba|nr1a1-A|thra-A|THR |
Gene, Accession # | Gene ID: 7067 |
Catalog # | ABIN361383 |
Price | |
Order / More Info | Thyroid Hormone Receptor, alpha (THRA) (Isotype a1), (Isotype a2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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