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Antigenic Specificity | Glial Fibrillary Acidic Protein (GFAP) (aa 411-422) |
Clone | S206B-9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | biotin conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC),Immunofluorescence (IF),Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia.Cellular Localization: Cytoplasm |
Immunogen | Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP, 100% identical in rat and mouse. >50% identity with other proteins (Vimentin, Desmin and Peripherin). |
Other Names | GFAP|AI836096|cb345|etID36982.3|gfapl|wu:fb34h11|wu:fk42c12|xx:af506734|zgc:110485 |
Gene, Accession # | Gene ID: 2670,14580,24387 |
Catalog # | ABIN1740974 |
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Order / More Info | Glial Fibrillary Acidic Protein (GFAP) (aa 411-422) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 2483104, 2459498 |
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