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| Product Name | CAMK1D, Active, Recombinant, Human (Calcium/Calmodulin-Dependent Protein Kinase Type 1D) |
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| Description | Purity ~90% (SDS-PAGE). Calcium/calmodulin-dependent protein kinase ID (CAMK1D), or a novel Ca2+/calmodulin-dependent kinase I-like kinase (CKLiK), showed kinase activity and that the activity was enhanced by Ca(2+) and calmodulin. Using a novel antibody generated against the C-terminus of CKLiK, CKLiK was detected in CD34+-derived neutrophils and eosinophils, as well as in mature peripheral blood granulocytes. Activation of human granulocytes by N-formyl-methionyl-leucyl-phenylalanine (fMLP) and platelet-activating factor (PAF), but not the phorbol ester PMA (phorbol 12-myristate-13-acetate), resulted in induction of CKLiK activity, in parallel with a rise of intracellular [Ca2+]. Furthermore, fMLP-induced neutrophil migration on albumin-coated surfaces was perturbed, as well as beta2-integrin-mediated adhesion. These findings suggest a critical role for CKLiK in modulating chemoattractant-induced functional responses in human granulocytes (1). Also, CAMK1D exhibits Ca(2+)/CaM-depende |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | camk 1d, camk-1d, Active CAMK1d, CAMK1d, CAMK1 delta, human CAMK1d, active kinase, active kinases, CAMK, recombinant CAMK1d, recombinant CAMK, kinase activity assay, protein kinas |
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| Gene, Accession, CAS # | CAMK1d, Gene ID: 8536, SwissProt: Q14012 |
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| Catalog # | 219514 |
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| Order / More Info | CAMK1D, Active, Recombinant, Human (Calcium/Calmodulin-Dependent Protein Kinase Type 1D) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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