| 产品详情 |
| Edit |   |
|---|
| Product Name | POLR3K, Recombinant, Human, aa1-108, His-SUMO-Tag (DNA-directed RNA Polymerase III Subunit RPC10) |
|---|
| Description | Purity ~90% (SDS-PAGE). DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Source: Recombinant protein corresponding to aa1-108 from human POLR3K, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~28.3kD AA |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | DNA-directed RNA Polymerase III Subunit RPC10, RNA Polymerase III Subunit C10, DNA-directed RNA Polymerase III Subunit K RNA Polymerase III 12.5kD Subunit, RPC12.5, RNA Polymerase III Subunit C11, HsC11p, RPC11, hRPC11, POLR3K, RPC11, My010 |
|---|
| Gene, Accession, CAS # | SwissProt: Q9Y2Y1 |
|---|
| Catalog # | 374792 |
|---|
| Price | |
|---|
| Order / More Info | POLR3K, Recombinant, Human, aa1-108, His-SUMO-Tag (DNA-directed RNA Polymerase III Subunit RPC10) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|