| 产品详情 |
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| Product Name | Sunitinib malate |
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| Description | MW: 110.2. Purity >98% (TLC); NMR conforms. VEGFR; PDGFR inhibitorSelective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50=40-90 nM) with >300-fold selectivity against related MAP kinases. Anti-inflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable. Active in vivo. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [SP-600125; Anthra [1-9-cd] pyrazol-6(2H)-one; 1,9-Pyrazoloanthrone] |
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| Gene, Accession, CAS # | CAS: 129-56-6 |
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| Catalog # | MBS515034 |
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| Order / More Info | Sunitinib malate from MYBIOSOURCE INC. |
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| Product Specific References | BL Bennett et al. Proc. Natl. Acad. Sci. USA. 2001 98:13681 M Rahman et al. Brain Res. 2012 1448:117 |
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