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| Product Name | Ran Activation Assay |
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| Description | Background: Small GTP-binding proteins (or GTPases) are a family of proteins that serve as molecular regulators in signaling transduction pathways. Ran, a 25 kDa protein of the Ras superfamily, regulates a variety of biological response pathways that include DNA synthesis, cell cycle progression, and translocation of RNA/proteins through the nuclear pore complex. Like other small GTPases, Ran regulates molecular events by cycling between an inactive GDP-bound form and an active GTP-bound form. I |
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| Size | 5 assays, 20 assays, |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS169121 |
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| Order / More Info | Ran Activation Assay from MYBIOSOURCE INC. |
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| Product Specific References | 1. Melchior, F., B. Paschal, J. Evans, and L. Gerace (1993) J. Cell Biol. 123:1649-1659.2. Moore, M.S., and G. Blobel (1993) Nature. 365:661-663.3. Bamba, C., Y. Bobinnec, M. Fukuda, and E. Nishida (2002) Curr. Biol. 12:503-507.4. Carazo-Salas, R.E., G. Guarguaglini, O.J. Gruss, A. Segref, E. Karsenti, and I.W. Mattaj (1999) Nature. 400:178-181.5. Dasso, M (2001) Cell. 104:321-324.1. Brasseur, A. et al. (2014). The bi-Lobe-Associated LRRP1 Regulates Ran Activity in Trypanosoma brucei. J Cell Sci. 127:4846-4856.2. Yuen, H. et al. (2013). RanGTPase: A Candidate for Myc-Mediated Cancer Progression. J Natl Cancer Inst. 105:475-488. |
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