| 产品详情 |
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| Product Name | Verdinexor |
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| Description | An inhibitor of XPO1/CRM1 with anticancer and antiviral activities; inhibits the growth of OCI-Ly3, OCI-Ly10, and CLBL1 DLBCL cells (IC50s = 2.1, 41.8, and 8.5 nM, respectively); inhibits XPO1/CRM1-mediated nuclear transport of RSV M protein at >1 µM; reduces RSV A2 replication (IC50 = 0.96 µM) without affecting viability of A549 cells (CC50 = >38 µM); reduces virus shedding, pulmonary TNF-α, IL-6, MCP01, and IFN-γ expression, and leukocyte infiltration into the bronchoalveolar space in a mouse model of influenza A viral infection at 20 mg/kg |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | KPT-335 |
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| Gene, Accession, CAS # | CAS: 1392136-43-4 |
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| Catalog # | 26171-10 |
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| Price | |
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| Order / More Info | Verdinexor from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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