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| Antigenic Specificity | Glial Fibrillary Acidic Protein (GFAP) (aa 417-432), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Glial fibrillary acidic protein(GFAP) is an intermediate-filament(IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human GFAP(417-432aa DGEVIKESKQEHKDVM), identical to the related rat sequence, and different from the related mouse sequence by two amino acids. |
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| Other Names | GFAP|AI836096|cb345|etID36982.3|gfapl|wu:fb34h11|wu:fk42c12|xx:af506734|zgc:110485 |
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| Gene, Accession # | Gene ID: 2670,14580,24387 |
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| Catalog # | ABIN343361 |
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| Price | |
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| Order / More Info | Glial Fibrillary Acidic Protein (GFAP) (aa 417-432), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 22749978, 21901549, 22661361, 22664874, 23111336, 22119193, 21842271, 21459105, 19548770, 20667013, 18721816, 17952134, 17532039, 16850748, 17120746, 15934296, 15473985, 23022502, 19111894, 2740350, 8893019, 2165732 |
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